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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare providers to select the right test the first time. Patients benefit from faster diagnosis and a more targeted treatment. Clinicians benefit from better antibiotic stewardship. Labs improve efficiency and cost savings. The BioFire FilmArray Pneumonia plus panel (PN panel) tests native sputum, endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens with clinical relevance and antimicrobial resistance genes, with semiquantitative results within an hour. Respiratory The burning of biomass (wood plants, trees and other organic materials) produces gaseous pollutants and fine particulate matter that negatively impact the respiratory system. Furthermore, the environmental issues caused by forest fires, such as droughts, can be potentiated by climate change, which can increase their negative impact on the human health. In the United States wildfire smoke is linked to hospitalizations due to respiratory diseases like asthma, COPD, and lung cancer. Additionally, this kind of air pollution is a risk factor for cardiovascular disease and a significant contributing factor to the burden of disease among the most vulnerable populations, including people who are of lower socioeconomic status (SES). In the COVID-19 pandemic, a number of communities were exposed to unhealthy levels of air pollution resulting from wildfires. However the public health response to this environmental issue has been limited and largely focused on communicating regarding symptom management. This knowledge gap is alarming given the evidence that smoking cigarettes and other causes of poor quality air can lead to health problems. Researchers are now evaluating the best ways to protect the public's health in future events of this kind. NIH is a research institution that studies this critical public health issue through the BLUE CORAL and FIRE CORAL studies. First time that a prospective study is conducted, it will assess the long-term effects of exposure to smoke from wildfires and other sources. FIRE CORAL is recruiting adult participants hospitalized for the index episode of COVID-19 who have a fluency in English or Spanish and are not pregnant. The protocol for FIRE CORAL includes a series of tests in-person that objectively measure pulmonary function testing and lung imaging, as well as functional assessment. The lungs are particularly sensitive to the effects of smoke and other particles because they can trigger or worsen chronic respiratory conditions like emphysema or COPD, and increase the risk of developing pneumonia. Smoke exposure can cause adverse effects on your health. To lessen or stop these effects, you should avoid outdoor activities and wear the EPA “N95” mask. This mask is designed to trap small particles. Smoking can cause irritation of the eyes and throat, and can cause an irritated nose. To reduce the symptoms, the lungs should be flushed with plenty of fluids and taking medications that decrease inflammation, like corticosteroids. Bloodstream The bloodstream is the first line of defense against germs that enter your system. Special cells called dendritic cells are akin to your fire department's call center. they collect the antigens (molecules that trigger an immune response) from invaders and release proteins to signal other white blood cells to come fight them. Circulating white blood cells, differentials, and band cells were elevated during firefighters' firefighting shifts, as compared to levels following physical exertion without firefighting. Skin Dermatologists were concerned that the smoke and ash that resulted from the California wildfires could cause an adverse effect on the skin of those who were exposed to them. Maria Wei, a graduate student at University of California, Irvine is researching how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22nd. Wei's research has shown that the temperature of the skin varies based on how long the body is exposed to flames. It can take as long as two hours for a skin to reach its flash point—the temperature at which it starts to burn and then turns to ash. This is why it's crucial to stay away from an open flame or campfire and why you must wear protective clothing when you are outside in the midst of a forest fire or even just a hot day. Forest fires will continue happen, despite the precautions implemented to reduce the risk of fires from causing pollution. Wei believes that as the climate changes cause forests to burn faster, the number of people who suffer from wildfires will grow. That means more people will be required to wear long sleeves, hats, and thick moisturizers. It's also important to know that the atopic dermatitis (itchy skin) that a lot of people suffer from is often exacerbated by wildfire air pollution. It is believed that this is because the particles in smoke can clog pores, making the atopic dermatitis condition worse. Another issue is the fact that atopic dermatitis tends to make people more sensitive to UV light, which can be aggravated by smoke from wildfires. This can cause people to be more likely to seek out tanning salons and can also cause people to tan less protection than they should. A fire and ice treatment can help reduce atopic skin conditions however it is not advised for anyone who has an open wound or rash. This treatment is not recommended for patients with active acne, or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial, at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges a mild facelift and a peel, but without the need for time off. It's designed to resurface the skin, alleviate rosacea symptoms, decrease acne scarring, reduce lines and wrinkles, and stimulate cellular renewal. This is a great treatment to provide your skin with a radiant glow. Infections The human body is a complex network of organs and tissues that work to shield us from infections. Infections are caused by microscopic microorganisms like parasites, viruses, bacteria and fungus that invade healthy cells and cause them to replicate beyond control. Your immune system can react by exhibiting symptoms of illness. These symptoms could range from a runny or stuffy nose to stomach upset however, they may also include a fever that is high swelling of the glands, an itchy rash. The type of infection and its location can impact the symptoms. Infections can spread in a variety of ways, but the most common are transmitted from person to person by droppings that hang in the air after sneezing or coughing. This is how bacterial illnesses like tuberculosis, strep, and meningococcal disease, as well as viral infections such a common cold and influenza are spread. Some infections caused by bacteria, such as skin infections and sexually transmitted infections (STIs) like gonorrhea and chlamydia are transmitted by contact with infected tissue or mucous membranes, or through indirect contact with contaminated surfaces. Certain bacterial diseases are transmitted by bugs like mosquitoes, ticks or fleas and can be spread when these bugs bite you. The virus and the parasites are small enough to get into your bloodstream and infect your cells which can cause serious illness like the common cold and AIDS. Fungi cause many skin conditions, like ringworm and athlete's foot, while some affect the lungs or the nervous system, such as the rabies virus. The BioFire PN Panel uses our innovative FilmArray technology to detect an extensive list of pathogens involved in upper respiratory infections in sputum or bronchoalveolar lavage fluid samples. The kit comes with a reagent pouch that stores all the necessary chemicals to perform reverse transcription PCR, multiplex nested testing and detection with a single device. This is a simple solution that assists clinicians identify and treat patients suffering from a variety respiratory symptoms. biofuel fireplace insert has been approved as an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.